Two fatal and four surviving cases after accidental infusion of ropivacaine

نویسندگان

چکیده

Abstract Purpose In this paper, we describe six cases, where patients were falsely treated with pre-filled ropivacaine solution instead of medical saline for postoperative settings. Two the died because fatal concentrations in blood, four survived no further physical injury, and two them showed typical intoxication symptoms. The collected blood urine samples deceased, as well surviving patients, analyzed laboratory routine screening. Methods Ropivacaine its main metabolite 3-OH-ropivacaine by gas chromatography–mass spectrometry. Results All cases positive results ropivacaine. Due to poorly secured sample material at hospital, quantitative examination could not be carried out. one case, there traceable urine. all metamizole was found traces piritramide amount within upper limits therapeutical treatment values. Patients lower more symptoms compared those higher active substances. Conclusions context symptom development intoxication, speed injection a very important factor cause cases. To our knowledge, these are first reported

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ژورنال

عنوان ژورنال: Forensic Toxicology

سال: 2021

ISSN: ['1860-8965', '1860-8973']

DOI: https://doi.org/10.1007/s11419-021-00574-x